DOXIL® (doxorubicin HCl liposome injection) is indicated for certain types of the time the drug is in the body; DOXIL® has more time to reach the tumor tissue, . No formal drug interaction studies have been conducted with DOXIL. Close. 8 USE IN SPECIFIC POPULATIONS. Doxil 50 mg/25 ml vial: xx. *Generic available from various manufacturers. VII. References. 1. Doxil [package insert]. Bedford, OH.

Author: Yozshugami Dagul
Country: France
Language: English (Spanish)
Genre: Marketing
Published (Last): 2 July 2008
Pages: 387
PDF File Size: 13.29 Mb
ePub File Size: 5.57 Mb
ISBN: 195-7-44670-697-2
Downloads: 30448
Price: Free* [*Free Regsitration Required]
Uploader: Mezirr

The scheduling of chemotherapy is set based on the type of cells, rate at which they divide, and the time at which a given drug is likely to be effective. Meaning low point, nadir is the point in time between chemotherapy cycles in which you experience low blood counts. Contact your health care provider within 24 hours of noticing any of the following: Different drugs may affect different parts of the body.

This insedt is classified as an “anthracycline antibiotic. A serious but uncommon side effect of doxorubicin – parent drug to doxorubicin liposomal – can be interference with the pumping action of the heart. The liposomes are pegylated with surface-bound methoxypolyethylene glycol MPEG to increase circulation time and protect them from detection by the mononuclear phagocyte system MPS. This page was last modified Your doctor will monitor your heart function.

Home Page |

If a drug has been approved for one use, physicians sometimes elect to use this same drug for other problems if they believe it might be helpful. Have questions about chemotherapy?

We encourage you to read the Privacy Policy of every website you visit. Our Privacy Policy is located at Doxil. The following inser require medical attention, but are not an emergency. However, in some cases, these reactions may be serious and sometimes life-threatening and may be fatal. Views Read View source View history. We strongly encourage you to talk with your health care professional about your specific medical condition and treatments.

Drugs Intravenous medications Irritant chemotherapy Liposomal chemotherapy Pegylated doxik Anthracyclines Topoisomerase inhibitors Breast cancer medications Burkitt lymphoma medications Diffuse large B-cell lymphoma medications Esophageal cancer medications Hemophagocytic lymphohistiocytosis medications HIV-associated lymphoma medications Hodgkin lymphoma medications Multiple myeloma medications Ovarian cancer medications Plasma cell leukemia medications Endometrial cancer medications Vascular sarcoma medications FDA approved in Cancer cells no longer have the normal checks and balances in place that control and limit cell division.


The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division.


Periodic blood work to monitor your complete blood count CBC as well as the function of other organs such as your kidneys and liver will also be ordered doxul your doctor. This “lifetime maximum dose” may be lower if you have heart disease risk factors such as radiation to the chest, advancing age, and use of other heart-toxic drugs. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis division. By clicking “OK” below, you will be taken to a website that may contain links or references to other websites to which our Privacy Policy may not apply.

The ultimate responsibility for patient care resides with a healthcare professional.

Navigation menu Personal tools Create account Log in. If you are pregnant, planning to become pregnant, or nursing, inform your doctor. Infusion-related side effects symptoms which may occur during the doxiil treatment include: Their nm size and long circulation may aid their ability to penetrate the altered vasculature of tumors.

Inform your doctor of any history of heart disease, radiation to your chest, or prior anticancer therapy. These drugs act during multiple phases of the cell cycle and are considered cell-cycle specific. You can receive only up to doxl certain amount of the parent drug, doxorubicin, during your lifetime. Doxil is the trade name for doxorubicin liposomal. No, I am not.

For information about the 4th Angel Mentoring Program visit www. These side effects are less common, meaning they occur inserh percent of patients receiving doxorubicin liposomal: You are encouraged to report negative side effects of prescription drugs to the FDA.

Please inform your doctor about your history of allergic reactions to medications or other substances. Be sure to tell your doctor immediately if you experience any of these or other symptoms.


Doxorubicin liposomal is used to treat AIDS-related Kaposi’s sarcoma, breast cancer, ovarian cancer, and other solid tumors. The “normal” cells will grow back and be healthy but in the meantime, side effects occur. There are packabe types of antitumor antibiotics:.

Doxorubicin Liposomal

There is a slight risk of developing a blood cancer such as leukemia years after taking drugs similar to doxorubicin liposomal. It is the drug doxorubicin dkxil in a closed lipid sphere liposome. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.

doxjl Cancerous cells lose this ability. Instead, for the most current information, please refer to your preferred pharmacopeias such as MicromedexLexicompUpToDate courtesy of Lexicomp pakcage, or the prescribing information. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The material on site is intended only as informational or as an educational aid and it is not intended to be insett as medical advice.

Chemotherapy drugs that affect cells when they are at rest are called cell-cycle non-specific. Antitumor antibiotics are made from natural products produced by species of the soil fungus Streptomyces. For most patients, these reactions have resolved within several hours to a day once the infusion is stopped, or for some patients with slowing of the infusion rate.

Doxorubicin Liposomal – Drug Information – Chemocare

doxul This may lead to tingling or burning, redness, flaking, bothersome swelling, small blisters, or small sores on palms of hands or soles of feet.

Exact mechanism of release of the active drug contained within the liposome is not understood. However, you should always inform your health care provider if you experience any unusual symptoms.